Publications
(undergraduate authors, co-first authors# )
95Quaternary Phosphonium Compounds: An Examination of Non-Nitrogenous Cationic Amphiphiles to Evade Disinfectant Resistance
94Antibacterials
Cheng, A. V.; Wuest, W.M.
2021 DOI: 10.1021/acs.infocus.7e4006 (Invited contributor for ACS In-Focus Series of E-books)
92Using membrane perturbing small molecules to target chronic persistent infections
Schrank, C.L.; Wilt, I.K.; Monteagudo, C.O.; Haney, B.A.; Wuest, W.M.*
RSC Medicinal Chemistry 2021 12, 1312 DOI: 10.1039/D1MD00151E (Invited Review)
91Promiscuous Pseudomonas: Uptake of non-endogenous ligands for iron acquisition
Kaplan, A.R.; Wuest, W.M.*
Tetrahedron Letters 2021 75, 153204 DOI: 10.1016/j.tetlet.2021.153204 (Tetrahedron Special Issue honoring Dale Boger)
90Mining for mouth metabolites
Scharnow, A.M.; Wuest, W.M.*
Nature Chemical Biology 2021 17, 505 DOI: 10.1038/s41589-021-00784-9 (Invited Highlight)
89An Efficient Synthesis of 3-Alkylpyridine Alkaloids Enables Their Biological Evaluation
Kaplan, A. R.#; Schrank, C.L.#; Wuest, W.M.*
ChemMedChem 2021 16, 2487 DOI: 10.1002/cmdc.202100134 (highlighted as a Very Important Paper; selected for cover art)
88The Silent Pandemic: Emergent Antibiotic Resistances Following the Global Response to SARS-CoV-2
Mahoney, A.R.; Safaee, M.M.; Wuest, W.M.; Furst, A.L.*
iScience 2021 24, 102304 DOI: 10.1016/j.isci.2021.102304
87Pyochelin Biosynthetic Metabolites Bind Iron and Promote Growth in Pseudomonas Demonstrating Siderophore-like Activity
Kaplan, A.R.; Musaev, D.G.; Wuest, W.M.*
ACS Infectious Diseases 2021 7, 544 DOI: 10.1021/acsinfecdis.0c00897
86Trivalent Sulfonium Compounds (TSCs): Tetrahydrothiophene-based amphiphiles exhibit similar antimicrobial activity to analogous ammonium-based amphiphiles
Feliciano, J.A.; Leitgeb, A.J.; Schrank, C.L.; Allen, R.A.; Wuest, W.M.*; Minbiole, K.P.C.*; Carden, R.G.*
Bioorg. Med. Chem. Lett. 2021 37, 127809 DOI: 10.1016/j.bmcl.2021.127809
85Broad Spectrum Antibiotic Xanthocillin X Effectively Kills Acinetobacter baumannii via Dysregulation of Heme Biosynthesis
Hubner, I.; Shapiro, J.A.; Hobmann, J.; Drechsel, J.; Hacker, S.M.; Rather, P.N.; Piepar, D.H.; Wuest, W.M.; Sieber, S.A.
ACS Central Science 2021 7, 488 DOI: 10.1021/acscentralsci.0c01621
84Building trans-bicyclo[4.4.0]decanes/decenes in complex multifunctional frameworks: the case for antibiotic development
Zhang, W.#; Kaplan, A.R.#; Davison, E.K.; Freeman, J.L.; Brimble, M.A.; Wuest, W.M.*
Natural Product Reports 2021 38, 880 DOI: 10.1039/DONP00052C
83Synthesis and biological evaluation of an antibacterial azaborine retinoid isostere
Haney, B.A.#; Schrank, C.L.#; Wuest, W.M.*
Tetrahedron Letters 2021 62, 152667 DOI:10.1016/j.tetlet.2020.152667 (Tetrahedron Special Issue honoring Dale Boger)
82Metallocene QACs: The Incorporation of Ferrocene Moieties into monoQAC and bisQAC Structures
Sommers, K.J.; Bentley, B.S.; Carden, R.G.; Post, S.J.; Allen, R.A.; Kontos, R.C.; Black, J.W.; Wuest, W.M.*; Minbiole, K.P.C.*
ChemMedChem 2021 16, 467 DOI: 10.1002/cmdc.20200605
80Advancements in the Development of Non-Nitrogen-Based Amphiphilic Antiseptics to Overcome Pathogenic Bacterial Resistance
Carden, R.G.*; Sommer, K.J.; Schrank, C. L.; Leitgeb, A.J.; Feliciano, J.A.; Wuest, W.M.*; Minbiole, K.P.C.*
ChemMedChem 2021 15, 1974 DOI:10.1002/cmdc.202000612
78A look around the West Indies: The spices of life are secondary metabolites
Demeritte, A.; Wuest, W.M.
Bioorg. Med. Chem. 2020 28, 115792 DOI: 10.1016/j.bmc.2020.115792 (Tetrahedron Young Investigator special issue honoring Emily Balskus)
77Asymmetric Total Synthesis of The Naturally Occurring Antibiotic Anthracimycin
Davison, E.; Freeman, J.; Zhang, W.; Wuest, W.M.; Furkert, D.; Brimble, M.*
Organic Letters 2020 22, 5550 DOI: 10.1021/acs/orglett/0c01913
76Are Quaternary Ammonium Compounds, the Workhorse Disinfectants, Effective against Severe Acute Respiratory Syndrome-Coronavirus-2?
Schrank, C.L.; Minbiole, K.P.C.*; Wuest, W.M.*
ACS Infectious Diseases 2020 6, 1553 DOI: 10.1021/acsinfecdis.0c00265