Publications
(undergraduate authors, co-first authors# )
118Total Synthesis of the Reported Structure of Cahuitamycin A: Insights into an Elusive Natural Product Scaffold
Justin A Shapiro, Savannah J Post, Gavin C Smith, William M Wuest
Org. Lett. 2023, 25, 51, 9243–9248
114Total synthesis and biological investigation of mindapyrroles A and B
Allen, R.; Wuest, W.M.*
ChemMedChem 2023 e202300235 DOI: 10.1002/cmdc.202300235 (Highlighted as a Very Important Paper)
99Total Synthesis and Antibacterial Investigations of 1-Hydroxyboivinianin A
Wilt, I.K.; Demeritte, A.R.; Wang, W.; Wuest, W.M.*
ChemMedChem 2022 17, e202200363. DOI: 10.1002/cmdc.202200363 (Highlighted as a Very Important Paper)
83Synthesis and biological evaluation of an antibacterial azaborine retinoid isostere
Haney, B.A.#; Schrank, C.L.#; Wuest, W.M.*
Tetrahedron Letters 2021 62, 152667 DOI:10.1016/j.tetlet.2020.152667 (Tetrahedron Special Issue honoring Dale Boger)
77Asymmetric Total Synthesis of The Naturally Occurring Antibiotic Anthracimycin
Davison, E.; Freeman, J.; Zhang, W.; Wuest, W.M.; Furkert, D.; Brimble, M.*
Organic Letters 2020 22, 5550 DOI: 10.1021/acs/orglett/0c01913
75Total synthesis of (+)-pilosinine via a stereodivergent conjugate addition strategy
Schrank, C.L.; Danneman, M.; Prebihalo, E.A.; Wuest, W.M.; Mullins, R.J.*
Tetrahedron Letters 2020 61 151945 DOI: 10..1016/j.tetlet.2020.151945
60Synthetic Simplification of Carolacton Enables Chemical Genetic Studies in Streptococcus mutans
Solinski, A.E.; Scharnow, A.M.; Fraboni, A.J., Wuest, W.M.*
ACS Infectious Diseases 2019 5, 1480 DOI:10.1021/acsinfecdis.9b00213
54An Investigation into Rigidity-Activity Relationships in bisQAC Amphiphilic Antiseptics
Kontos, R.C.; Schallenhammer, S.A.; Bentley, B.S.; Morrison, K.R.; Feliciano, J.A.; Tasca, J.A.; Kaplan, A.R.; Bezpalko, M.W.; Kassel, S.W.; Wuest, W.M.*; Minbiole, K.P.C.*
ChemMedChem 2019 14, 83 DOI: 10.1002/cmdc.201800622
50Epoxy isonitriles, a unique class of antibiotics – Synthesis of their metabolites and biological investigations
Ernouf, G.; Wilt, I.K.; Zahim, S.; Wuest, W.M.*
ChemBioChem 2018 19, 2448 (Selected for ChemBio Talents Issue) DOI: 10.1002/cbic
49Biologically Inspired Total Synthesis of Ulbactin F, an Iron-Binding Natural Product
Shapiro, J.A.#; Morrison, K.R.#; Chodisetty, S.S.; Musaev, D.G.; Wuest, W.M.*
Org. Lett. 2018 20, 5922. DOI: 10.1021/acs.orglett.8b02599
43Diverted Total Synthesis of the Baulamycins and Analogues Reveals an Alternate Mechanism of Action
Steele, A.D.; Ernouf, G.; Lee, Y-E.; Wuest, W.M.*
Organic Letters 2018 20, 1126 DOI: 10.1021/acs.orglett.8b00054
42Promysalin Elicits Species-Selective Inhibition of Pseudomonas aeruginosa by Targeting Succinate Dehydrogenase
Keohane, C.E.; Steele, A.D.; Fetzer, C.; Khowsathit, J.; Van Tyne, D.; Moynie, L.; Gilmore, M.S.; Karanicolas, J.; Sieber, S.A.; Wuest, W.M.*
J. Am. Chem. Soc. 2018 140, 1774 DOI: 10.1021/jacs.7b11212
41Honokiol-Inspired Analogs as Inhibitors of Oral Bacteria
Solinski, A.E.#; Ochoa, C.#; Lee, Y-E.; Paniak, T.; Kozlowski, M.C.*; Wuest, W.M.*
ACS Infectious Diseases 2018 4, 118 DOI:10.1021/acsinfecdis.7b00178
35Diverted Total Synthesis of Carolacton-Inspired Analogs Yields Three Distinct Phenotypes in Streptococcus mutans Biofilms
Solinski, A.E.#; Koval, A.B.#; Brzozowski, R.S.#; Morrison, K.R.; Fraboni, A.J.; Carson, C.E.; Eshraghi A.R.; Zhou, G.; Quivey, R.G.; Voelz, V.A.; Buttaro, B.A.; Wuest. W.M.*
J. Am. Chem. Soc. 2017 139, 7188. DOI: 10.1021/jacs.7b03879
27Diverted Total Synthesis of Promysalin Analogs Demonstrates that an Iron-Binding Motif is Responsible for its Narrow-spectrum Antibacterial Activity
Steele, A.D.; Keohane, C.E.; Knouse, K.W.; Rossiter, S.E.; Williams, S.J.; Wuest, W.M.*
J. Am. Chem. Soc. 2016 138, 5833. DOI: 10.1021/jacs.6b03373
25The Enantioselective Synthesis and Biological Evaluation of Chimeric Promysalin Analogs Facilitated by Diverted Total Synthesis
Knouse, K.W.; Wuest, W.M
J. Antibiotics 2016 69, 337. DOI: 10.1038/ja.2016.4 (invited paper for Amos B. Smith, III issue)
20Total Synthesis and Biological Evaluation of (-)-Promysalin
Steele, A.D.; Knouse, K.W.; Keohane, C.E.; Wuest, W.M.*
J. Am. Chem. Soc. 2015 137, 7314. DOI: 10.1021/jacs.5b04767
15Synthesis of cyclic dimeric methyl morpholinoside – a common synthetic precursor to cyclic dinucleotide analogs.
Kinzie, C.R.; Steele, A.D.; Pasciolla, S.M.; Wuest, W.M.*
Tetrahedron Lett. 2014 55, 4966. DOI: 10.1016/j.tetlet.2014.07.038
9A Concise Synthesis of Carolacton
Hallside, M.S.; Brzozowski, R.S.; Wuest, W.M.*; Phillips, A.J.*
Org. Lett. 2014 16, 1148.
Highlighted by Org. Lett. as a top 10 accessed article from Jan-Jun 2014