Publications
(undergraduate authors, co-first authors# )
112Antimicrobial activity of a new class of synthetic retinoid antibiotics and comparator agents against ocular staphylococci
111Structure-based Design of Promysalin Analogues to Overcome Mechanisms of Bacterial Resistance
Mahoney, A.R.; Storek, K.M.; Wuest, W.M.*
ACS Omega 2023 8, 12558-12564. DOI: 10.1021/acsomega.3c00884
110Biological Evaluation of the Antibacterial Retinoid CD437 in Cutibacterium acnes Infection
Huang, X.; Pan, W.; Zhong, M-Z.; Chhonker. Y.S.; Steele, A.D.; Keohane, C.E.; Mishra, B.; Lucas, O.F.R.; Murry. D.J.; Ausubel, F.M.; Wuest. W.M.; Li, C-X.; Mylonakis. E.*
Antimicrobial Agents and Chemotherapy 2023 67, e10679-22 DOI: 10.1128/aac.01679-22
109Di-berberine conjugates as chemical probes of Pseudomonas aeruginosa MexXY-OprM efflux function and inhibition.
Kavanaugh. L.G.#; Mahoney, A.R.#; Dey, D.; Wuest, W.M.*; Conn, G.L.
npj Antimicrob Resist 1, 12 (2023). https://doi.org/10.1038/s44259-023-00013-4
108Soft QPCs: Biscationic Quaternary Phosphonium Compounds as Soft Antimicrobial Agents
Brayton, S.R.; Toles, Z.E.A.; Sanchez, C.A.; Michaud, M.E.; Thierer L.M.; Keller, T.M.; Risener, C.J.; Quave, C.L.; Wuest, W.M.*; Minbiole, K.P.C.*
ACS Infectious Diseases 2023 9, 943-951. DOI: 10.1021/acsinfecdis.2c00624
107Double BAC and Triple BAC: A Systematic Analysis of the Disinfectant Properties of Multicationic Derivatives of Benzylalkonium Chloride (BAC)
Toles, Z.E.A.; Wu, A.; Sanchez, C.A.; Michaud, M.E.; Thierer, L.M.; Wuest, W.M.*; Minbiole, K.P.C.*
ChemMedChem 2023 18, e202300018 DOI: 10.1002/cmdc.202300018
106Ribosome-Targeting Antibiotics and Resistance via Ribosomal RNA Methylation
Jeremia, L.; Deprez, B.; Dey, D.; Conn, G.L.*; Wuest, W.M.*
RSC Medicinal Chemistry 2023 14, 624-643. (Invited Review for Special Issue on Antibiotic Resistance) DOI: 10.1039/D2MD00459C
105Atom Economical QPCs: Phenyl-free Biscationic Quaternary Phosphonium Compounds as Potent Disinfectants
Thierer, L.M.; Peterson, A.A.; Michaud, M.E.; Sanchez, C.A.; Brayton, S.; Wuest, W.M.*; Minbiole, K.P.C.*
ACS Infectious Diseases 2023 9, 609-616. DOI: 10.1021/acsinfecdis.2c00575
104Beyond ergosterol: Strategies for combatting antifungal resistance in Aspergillus fumigatus and Candida auris
Cruz, R.; Wuest, W.M.*
Tetrahedron 2023, 133268-133280 DOI: 10.1016/j.tet.2023.133268 (Tetrahedron Special Issue Honoring Prof. John Wood)
103Property-Controllable Generation of Quaternary Ammonium Compounds
Pan, B.; Wang, Y.; Lin, X.; Qin, M.; Ghaemi, S.; Ding, A.; Wang, S.; Al-Khalifa, S.; Minbiole, K.P.C.; Wuest, W.M.; Petersen, A.A.; Leitgeb, A.; Shehu, A.;* Zhao, L.*
IEEE Intl Conf on Bioinformatics and Biomedicine (BIBM) Workshops: Computational Structural Biology Workshop (CSBW). 2022 :1-8.
102Generation and Characterization of Quaternary Ammonium Compounds via Deep Learning
Wang, Y.; Ghaemi, S.; Ding, A.; Du, Y.; Pan, B.; Qin, M.; Lin, X.; Petersen, A.A.; Leitgeb, A.; Al-Khalifa, S.; Minbiole, K.P.C.; Wuest, W.M.; Zhao, L.;* Shehu, A.*
IEEE Intl Conf on Bioinformatics and Biomedicine (BIBM) Workshops: Computational Structural Biology Workshop (CSBW). 2022 :1-8.
101Multi-objective Deep Data Generation with Correlated Property Control
Wang, S.; Guo, X.; Ling, M.; Pan, B.; Du, Y.; Wang, Y.; Ye, Y.; Petersen, A.A.; Leitgeb, A.; Al-Khalifa, S.; Minbiole, K.P.C.; Wuest, W.M.; Shehu, A.*; Zhao, L.*
Advances in Neural Information Processing Systems (NeurIPS). 2022 Available here
100Quaternary Phosphonium Compound Unveiled as a Potent Disinfectant against Highly Resistant Acinetobacter baumannii Clinical Isolates
Michaud, M.E.; Allen, R.A.; Morrison-Lewis. K.R.; Sanchez, C.A.; Minbiole, K.P.C.*; Post, S.J.*; Wuest, W.M.*
ACS Infectious Diseases 2022 8, 2307-2314 DOI: 10.1021/acsinfecdis.2c00382
99Total Synthesis and Antibacterial Investigations of 1-Hydroxyboivinianin A
Wilt, I.K.; Demeritte, A.R.; Wang, W.; Wuest, W.M.*
ChemMedChem 2022 17, e202200363. DOI: 10.1002/cmdc.202200363 (Highlighted as a Very Important Paper)
98Rigidity-Activity Relationships of bisQPC Scaffolds against Pathogenic Bacteria
Spahr, A.C.; Michaud, M.E.; Amoo, L.E.; Sanchez, C.A.; Hogue, C. E.; Thierer, L.M.; Gau, M.R.; Wuest, W.M.*; Minbiole, K.P.C.*
ChemMedChem 2022 17, e202200224. DOI: 10.1002/cmdc.202200224
97Exploration of inhibitors of the bacterial LexA repressor-protease
Cheng, A.V.C.#; Cory, M.B.#; Li, A.; Kohli, R.M.*; Wuest, W.M.*
Bioorg. Med. Chem. Lett. 2022 65, 128702. DOI: 10.1016/j.bmcl.2022.128702
96nTZDpa (non-thiazolidinedione PPARγ partial agonist) derivatives retain antimicrobial activity without improving renal toxicity
Dekarske, M.M.; Felix, L.O.; Ortiz, C.O.; Csatary, E.E.; Mylonakis, E.; Wuest, W.M.*
Bioorg. Med. Chem. Lett. 2022 64, 128678. DOI: 10.1016/j.bmcl.2022.128678
95Quaternary Phosphonium Compounds: An Examination of Non-Nitrogenous Cationic Amphiphiles to Evade Disinfectant Resistance
Sommers, K.J.#; Michaud, M.E.#; Hogue, C.E.; Scharnow, A.M.; Amoo, L.E.; Peterson, A.A.; Carden, R.G.; Minbiole, K.P.C.*; Wuest. W.M.*
ACS Infectious Diseases 2022 8, 387. DOI: 10.1021/acsinfecdis.1c00611
94Antibacterials
Cheng, A. V.; Wuest, W.M.
2021 DOI: 10.1021/acs.infocus.7e4006 (Invited contributor for ACS In-Focus Series of E-books)
