Publications

(undergraduate authors, co-first authors# )

130Microbial Changes Occurring During Oronasal Fistula Wound Healing

Steven L. Goudy*, Heath L. Bradley, Camilo Anthony Gacasan, Afra Toma, Keerthi Priya Chinniampalayam Sekar, William M. Wuest, Martin Tomov, Vahid Serpooshan, Ahmet Coskun and Rheinallt M. Jones Microorganisms 202513(2), 327

127Adaptations to cationic biocide exposure differentially influence virulence factors and pathogenicity in Pseudomonas aeruginosa

Germán G Vargas-Cuebas, Christian A Sanchez, Elise L Bezold, Gabrielle M Walker, Shehreen Siddiqui, Kevin PC Minbiole, William M Wuest

Virulence, 2024, 15, 2397503.

126Highly Effective Biocides against Pseudomonas aeruginosa Reveal New Mechanistic Insights Across Gram-Negative Bacteria

Christian A Sanchez, Germán G Vargas-Cuebas, Marina E Michaud, Ryan A Allen, Kelly R Morrison-Lewis, Shehreen Siddiqui, Kevin PC Minbiole, William M Wuest

 

ACS Infect. Dis. 2024, 10, 11, 3868–3879

124Exploring the Correlation of Dynamic Surface Tension with Antimicrobial Activities of Quaternary Ammonium-Based Disinfectants

Germán G. Vargas-CuebasDr. Christian A. SanchezSamantha R. BraytonAlexander NikoloffDr. Ronald MastersProf. Kevin P. C. MinbioleProf. William M. Wuest

ChemMedChem, 2024, 19, e202400262

116Investigating the Role of Metabolism for Antibiotic Combination Therapies in Pseudomonas aeruginosa

 

 

MM Golden, SJ Post, R Rivera, WM Wuest

 

ACS Infectious Diseases 9 (12), 2386-2393

100Quaternary Phosphonium Compound Unveiled as a Potent Disinfectant against Highly Resistant Acinetobacter baumannii Clinical Isolates

Michaud, M.E.; Allen, R.A.; Morrison-Lewis. K.R.; Sanchez, C.A.; Minbiole, K.P.C.*; Post, S.J.*; Wuest, W.M.*

 

ACS Infectious Diseases 2022 8, 2307-2314 DOI: 10.1021/acsinfecdis.2c00382

74The histone-like protein AlgP regulon is distinct in mucoid and nonmucoid Pseudomonas aeruginosa and does not include alginate biosynthesis genes

Cross, A.R.; Csatary, E.E.; Raghuram, V.; Diggle, F.L.; Whiteley, M.; Wuest, W.M.; Goldberg, J.B.*

 

Microbiology 2020 DOI: 10.1099/mic/0/000923

61Combined inhibition of Aurora A and p21-activated kinase 1 as a new treatment strategy in breast cancer

Korobeynikov, V.; Borakove, M.; Feng, Y.; Wuest, W.M.; Koval, A.B.; Nikonova, A.S.; Serebriiskii, I.; Chernoff, J.; Borges, V.F.; Golemis, E.A.; Shagisultanova, E.*

 

Breast Cancer Research & Treatment 2019 117, 369 DOI:10.1007/s10549-019-05329-2

 

 

60Synthetic Simplification of Carolacton Enables Chemical Genetic Studies in Streptococcus mutans

Solinski, A.E.; Scharnow, A.M.; Fraboni, A.J., Wuest, W.M.*

 

ACS Infectious Diseases 2019 5, 1480 DOI:10.1021/acsinfecdis.9b00213

 

 

59The natural product elegaphenone potentiates antibiotic effects against Pseudomonas aeruginosa

Zhao, W.; Cross, A.R.; Crowe-McAuliffe, C.; Weigert-Munoz, A.; Csatary, E.E.; Solinski, A.E.; Krysiak, J.; Goldberg, J.B.; Wilson, D.N.; Medina, E.; Wuest, W.M.; Sieber S.A.*

 

Angew. Chem. Int. Ed. 2019 58, 8581 DOI: 10.1002/anie.201903472

 

 

53Identification of Specific and Non-specific Inhibitors of Bacillus anthracis Type III Pantothenate Kinase (PanK)

Shapiro, J.A.; Varga, J.J.; Parsonage, D.; Walton, W.; Redinbo, M.R.; Ross, L.J.; White, E.L.; Bostwick, R.*; Wuest, W.M.*; Clairborne, A.*; Goldberg, J.B.*

 

ChemMedChem 2019 14, 78 DOI: 10.1002/cmdc.201800652

 

 

48Discovery and Optimization of nTZDpa as an Antibiotic Effective Against Bacterial Persisters

Kim, W.; Steele, A.D.; Zhu, W.; Csatary, E.E.; Fricke, N.; Dekarske, M.M.; Jayamani, E.; Pan, W.; Kwon, B.; Sinitsa, I.F.; Rosen, J.; Conery, A.L.; Fuchs, B.B.; Vlahovska, P.M.; Ausubel, F.M.; Gao, H.; Wuest, W.M.*; Mylonakis, E.

 

ACS Infectious Diseases 2018 4, 1540 DOI: 10.1021/acsinfecdis.8b00161

 

 

47Transcriptomic profiling suggest that Promysalin alters metabolic flux, motility, and iron regulation in Pseudomonas putida KT2440

Giglio, K.; Keohane, C.E.; Stodghill, P.; Steele, A.D.; Fetzer, C.; Sieber, S.A.; Filiatrault, M.J.*; Wuest, W.M.*

 

ACS Infectious Diseases 2018 4, 1179. DOI: 10.1021/acsinfecdis.8b00041

 

 

46A new class of synthetic retinoid antibiotics effective against bacterial persisters

Kim, W.; Zhu, W.; Hendricks, G.L.; Van Tyne, D.; Steele, A.D.; Keohane, C.E.; Fricke, N.; Conery, A.L.; Shen, S.; Pan, W.; Lee, K.; Rajamuthiah, R.; Fuchs, B.B.; Vlahovska, P.M.; Wuest, W.M.; Gilmore, M.S.; Gao, H.; Ausubel, F.M.; Mylonakis, E.

 

Nature 2018 556, 103.  DOI: 10.1038/nature26157

 

 

45Claramines: A new class of broad-spectrum antimicrobial agents with bimodal activity

Blanchet, M.; Borselli, D.; Rodallec, A.; Peiretti, F.; Vidal, N.; Bolla, J.M.; Digiorgio, C.; Morrison, K.R.; Wuest, W.M.; Brunel, J.M*

 

ChemMedChem 2018 13, 1018 DOI: 10.1002/cmdc.201800073

 

44A dual inhibitor of Staphylococcus aureus virulence and biofilm attenuates expression of major toxins and adhesins

Hofbauer, B.; Vomacka, J.; Stahl, M.; Korotkov, V.; Jennings, M.C.; Wuest, W.M.; Sieber, S.A.*

 

Biochemistry 2018 57, 1814DOI: 10.1021/acs.biochem.7b01271

41Honokiol-Inspired Analogs as Inhibitors of Oral Bacteria

Solinski, A.E.#; Ochoa, C.#; Lee, Y-E.; Paniak, T.; Kozlowski, M.C.*; Wuest, W.M.*

 

ACS Infectious Diseases 2018 4, 118 DOI:10.1021/acsinfecdis.7b00178

40Hybrid BisQACs: Potent Biscationic Quaternary Ammonium Compounds Merging the Structures of Two Commercial Antiseptics

Schallenhammer, S.A.; Duggan, S.M.; Morrison, K.R.; Bentley, B.S.; Wuest, W.M.*; Minbiole, K.P.C.*

 

ChemMedChem 2017 12, 1931 DOI: 10.1002/cmdc.201700597

39ErosS enzyme from Aliivibrio fischeri plays Cupid to choanoflagellates

Rossiter, S.E.; Wuest, W.M.*

ChemBioChem 2017 18, 2298 DOI: 10.1002/cbic.201700552 (Invited Highlight)

37Efflux Pumps May Not Be the Major Drivers of QAC Resistance in Methicillin-Resistant Staphylococcus aureus

Jennings, M.C.; Forman, M.E.; Duggan, S.M.; Minbiole, K.P.C.*; Wuest, W.M.*

 

ChemBioChem 2017 18, 1573 DOI: 10.1002/cbic.201700233 (highlighted as a Very Important Paper, Selected as Cover Art)