Publications
(undergraduate authors, co-first authors# )
131From Natural Products to Small Molecules: Recent Advancements in Anti-MRSA Therapeutics
129Recent developments in antimicrobial small molecule quaternary phosphonium compounds (QPCs) – synthesis and biological insights
Diana McDonough, Christian A. Sanchez, William M. Wuest* and Kevin P. C. Minbiole
RSC Medicinal Chemistry., 2025, Advance Article
122Siderophores: A Case Study in Translational Chemical Biology
Andrew R. LeBlanc and William M. Wuest.
Published as part of Biochemistry virtual special issue “A Tribute to Christopher T. Walsh”.
Biochemistry, 2024, 63, 1877
119Metal chelation as an antibacterial strategy for Pseudomonas aeruginosa and Acinetobacter baumannii
Martina M. Golden a, Amelia C. Heppe a, Cassandra L. Zaremba *c and William M. Wuest
RSC Chem. Biol., 2024, 5, 1083
106Ribosome-Targeting Antibiotics and Resistance via Ribosomal RNA Methylation
Jeremia, L.; Deprez, B.; Dey, D.; Conn, G.L.*; Wuest, W.M.*
RSC Medicinal Chemistry 2023 14, 624-643. (Invited Review for Special Issue on Antibiotic Resistance) DOI: 10.1039/D2MD00459C
104Beyond ergosterol: Strategies for combatting antifungal resistance in Aspergillus fumigatus and Candida auris
Cruz, R.; Wuest, W.M.*
Tetrahedron 2023, 133268-133280 DOI: 10.1016/j.tet.2023.133268 (Tetrahedron Special Issue Honoring Prof. John Wood)
92Using membrane perturbing small molecules to target chronic persistent infections
Schrank, C.L.; Wilt, I.K.; Monteagudo, C.O.; Haney, B.A.; Wuest, W.M.*
RSC Medicinal Chemistry 2021 12, 1312 DOI: 10.1039/D1MD00151E (Invited Review)
90Mining for mouth metabolites
Scharnow, A.M.; Wuest, W.M.*
Nature Chemical Biology 2021 17, 505 DOI: 10.1038/s41589-021-00784-9 (Invited Highlight)
88The Silent Pandemic: Emergent Antibiotic Resistances Following the Global Response to SARS-CoV-2
Mahoney, A.R.; Safaee, M.M.; Wuest, W.M.; Furst, A.L.*
iScience 2021 24, 102304 DOI: 10.1016/j.isci.2021.102304
84Building trans-bicyclo[4.4.0]decanes/decenes in complex multifunctional frameworks: the case for antibiotic development
Zhang, W.#; Kaplan, A.R.#; Davison, E.K.; Freeman, J.L.; Brimble, M.A.; Wuest, W.M.*
Natural Product Reports 2021 38, 880 DOI: 10.1039/DONP00052C
80Advancements in the Development of Non-Nitrogen-Based Amphiphilic Antiseptics to Overcome Pathogenic Bacterial Resistance
Carden, R.G.*; Sommer, K.J.; Schrank, C. L.; Leitgeb, A.J.; Feliciano, J.A.; Wuest, W.M.*; Minbiole, K.P.C.*
ChemMedChem 2021 15, 1974 DOI:10.1002/cmdc.202000612
78A look around the West Indies: The spices of life are secondary metabolites
Demeritte, A.; Wuest, W.M.
Bioorg. Med. Chem. 2020 28, 115792 DOI: 10.1016/j.bmc.2020.115792 (Tetrahedron Young Investigator special issue honoring Emily Balskus)
71Phylogeny-guided Approach Yields Glycopeptides with Unique Action
Cheng, A.V.; Wuest, W.M.*
Trends in Pharmacological Sciences 2020 41, 297 DOI: 10.1016/j.tips.2020.03.002 (Invited Highlight)
62More QACs, more questions: recent advances in structure activity relationships and hurdles in understanding resistance mechanism
Morrison, K.R.; Allen, R.; Minbiole, K.P.C.*; Wuest, W.M.*
Tetrahedron Letters 2019 60, 150935 (Invited Digest) DOI: 10.1016/j.tetlet.2019.07.026
56Connecting iron acquisition and biofilm formation in the ESKAPE pathogens as a strategy for combatting antibiotic resistance
Post, S.J.; Shapiro, J.A.; Wuest, W.M.*
MedChemComm 2019 10, 505 (Invited review for the Antibiotic Resistance Issue) DOI: 10.1039/C9MD000032A
55Targeting S. mutans biofilms: A perspective on preventing dental caries
Scharnow, A.M.; Solinski, A.E.; Wuest, W.M.*
MedChemComm 2019 10 , 1057 (Invited review for the New Talent Collection) DOI: 10.1039/C9MD00015A
52From General to Specific: Can Primary Metabolism in Pseudomonas be Exploited for Narrow-Spectrum Antibiotics?
Shapiro, J.A.; Kaplan, A.R.; Wuest, W.M.*
ChemBioChem 2019 20, 34 DOI: 10.1002/cbic.201800383 (Invited Concept, highlighted in the 20th Anniversary Issue)
38Natural Products as Platforms to Overcome Antibiotic Resistance
Rossiter, S.E.; Fletcher, M.H.; Wuest, W.M.*
Chemical Reviews 2017 117, 12415 DOI: 10.1021/acs.chemrev.7b00283