Publications
(undergraduate authors, co-first authors# )
72Target-based design of promysalin analogs identifies a new putative binding cleft in succinate dehydrogenase
70Addition of ethylamines to the phenols of bithionol and synthetic retinoids does not elicit activity in gram-negative bacteria
Cheng, A.V.#; Schrank, C.L.#; Escobar, I.E.; Mylonakis, E.; Wuest, W.M.*
Bioorg. Med. Chem. Lett. 2020 30, 127099 DOI: 10.1016/j.bmcl.2020.127099
68Further Investigations into Rigidity-Activity Relationships in BisQAC Amphiphilic Antiseptics
Leitgeb, A.J.; Feliciano, J.A.; Sanchez, H.; Allen, R.A.; Morrison, K.R.; Sommers, K.J.; Carden, R.; Wuest, W.M.*; Minbiole, K.P.C.*
ChemMedChem 2020 15, 1510 DOI: 10.1002/cmdc.201900662
66Structure-Activity Relationship and Anticancer Profile of Second-Generation Anti-MRSA Synthetic Retinoids
Cheng, A.V.; Kim, W.; Escobar, I.E.; Mylonakis, E.; Wuest, W.M.*
ACS Med. Chem. Lett. 2020 11, 393 DOI: 10.1021/acsmedchemlett.9b00159 (Featured in the Women of Medicinal Chemistry Issue)
64A bisphenolic honokiol analog outcompetes oral antimicrobial agent cetylpyridinium chloride via a membrane-associated mechanism
Ochoa, C.#; Solinski, A.E.#; Nowlan, M.; Dekarske, M.M.; Wuest, W.M.*; Kozlowski, M.C.*
ACS Infectious Diseases 2020 6, 74 DOI: 10.1021/acsinfecdis.9b00190
61Combined inhibition of Aurora A and p21-activated kinase 1 as a new treatment strategy in breast cancer
Korobeynikov, V.; Borakove, M.; Feng, Y.; Wuest, W.M.; Koval, A.B.; Nikonova, A.S.; Serebriiskii, I.; Chernoff, J.; Borges, V.F.; Golemis, E.A.; Shagisultanova, E.*
Breast Cancer Research & Treatment 2019 117, 369 DOI:10.1007/s10549-019-05329-2
35Diverted Total Synthesis of Carolacton-Inspired Analogs Yields Three Distinct Phenotypes in Streptococcus mutans Biofilms
Solinski, A.E.#; Koval, A.B.#; Brzozowski, R.S.#; Morrison, K.R.; Fraboni, A.J.; Carson, C.E.; Eshraghi A.R.; Zhou, G.; Quivey, R.G.; Voelz, V.A.; Buttaro, B.A.; Wuest. W.M.*
J. Am. Chem. Soc. 2017 139, 7188. DOI: 10.1021/jacs.7b03879
34Ester- and Amide-containing MultiQACs: Exploring Multicationic Soft Antimicrobial Agents
Allen, R.A.; Jennings, M.C.; Mitchell, M.A.; Al-Khalifa, S.E.; Wuest, W.M.*; Minbiole, K.P.C.*
Bioorg. Med. Chem. Lett. 2017 27, 2107. DOI: 10.1016/j.bmcl.2017.03.077
28From Antimicrobial Activity to Mechanism of Resistance: The Multifaceted Role of Simple Quaternary Ammonium Compounds in Bacterial Eradication
Minbiole, K.P.C.*; Jennings, M.C.; Ator, L.E.; Black, J.W.; Grenier, M.C.; LaDow, J.E.; Caran, K.L.; Seifert, K.; Wuest, W.M.*
Tetrahedron 2016 72, 3559. DOI: 10.1016/j.tet.2016.01.014
19Quaternary Ammonium Compounds: An Antimicrobial Mainstay and Platform for Innovation to Address Bacterial Resistance
Jennings, M.C.; Minbiole, K.P.C.; Wuest, W.M.*
ACS Infectious Diseases, 2015 1, 288