The Wuest Lab

Slaying Superbugs at Emory University

Statistics

13

patents

11

people

120

PAPERS

About Us

Natural product total synthesis
Medicinal chemical biology

We synthesize natural products with interesting antibacterial activity to identify their biological targets. Using synthetic chemistry, we build derivatives of these compounds to optimize their potency and then use microbiological techniques to investigate their effects on pathogenic species such as Staphylococcus aureusPseudomonas aeruginosaAcinetobacter baumannii, and Streptococcus mutans.

Addressing the lack of diversity in STEM is a crucial step in eliminating sexism, racism, ableism, and other forms of discrimination in broader society. As a lab, we recognize that diversity breeds innovation and creativity by capitalizing on unique perspectives. We are committed to fostering an inclusive environment through increasing our personal awareness as well as promoting the advancement of people historically excluded from STEM disciplines. The Wuest Lab aspires to be a welcoming community for students and postdocs from any background.

Explore Our Research

Chemical Biology

Chemical Biology

Understand how our molecules exert their antimicrobial activity through in-house biological assays and collaborations

Microbiology

Microbiology

Use our knowledge of chemistry to study bacterial processes

Medicinal Chemistry

Medicinal Chemistry

Repurpose old drugs on novel targets and/or identify new compoundsto inhibit validated targets

Total Synthesis

Total Synthesis

Total synthesis and biological investigation of natural products with promising futures as antimicrobial agents